This study is an expansion by AI of nine public texts on ageing and the evidence that it can be slowed. One is a work of the United States government, in the public domain: the programme page of PROSPR at the Advanced Research Projects Agency for Health. Eight are articles published under a Creative Commons Attribution licence (seven under CC BY 4.0, one under CC BY 2.0), read in full from PubMed Central. Every passage in a block quote is one of these texts, word for word, and its source line names the saved file; the rest is AI writing. Findings are reported as their authors state them, with the limits they state. Nothing here is medical, clinical, nutritional, regulatory or investment advice. The readings through the works named are this study's interpretation.
| Text | Licence | Address |
|---|---|---|
| PROSPR: Proactive Solutions for Prolonging Resilience (ARPA-H program page) (2025), sources/arpa-h-prospr-program-page.md | Public domain (US government work) | https://arpa-h.gov/explore-funding/programs/prospr |
| The aging-disease false dichotomy: understanding senescence as pathology (2015), sources/gems-2015-aging-disease-false-dichotomy.md | CC BY 4.0 | https://pmc.ncbi.nlm.nih.gov/articles/PMC4468941/ |
| The economic value of targeting aging (2021), sources/scott-2021-economic-value-targeting-aging.md | CC BY 4.0 | https://pmc.ncbi.nlm.nih.gov/articles/PMC10154220/ |
| Healthy life extension: Geroscience’s north star (2026), sources/barzilai-2026-healthy-life-extension-geroscience.md | CC BY 4.0 | https://pmc.ncbi.nlm.nih.gov/articles/PMC13285945/ |
| DNA methylation age of human tissues and cell types (2013), sources/horvath-2013-dna-methylation-age-human.md | CC BY 2.0 | https://pmc.ncbi.nlm.nih.gov/articles/PMC4015143/ |
| Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm (2020), sources/belsky-2020-quantification-pace-biological-aging.md | CC BY 4.0 | https://pmc.ncbi.nlm.nih.gov/articles/PMC7282814/ |
| Reversal of epigenetic aging and immunosenescent trends in humans (2019), sources/fahy-2019-reversal-epigenetic-aging-immunosenescent.md | CC BY 4.0 | https://pmc.ncbi.nlm.nih.gov/articles/PMC6826138/ |
| Caloric restriction improves health and survival of rhesus monkeys (2017), sources/mattison-2017-caloric-restriction-improves-health.md | CC BY 4.0 | https://pmc.ncbi.nlm.nih.gov/articles/PMC5247583/ |
| Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (2023), sources/waziry-2023-effect-long-term-caloric.md | CC BY 4.0 | https://pmc.ncbi.nlm.nih.gov/articles/PMC10148951/ |
The texts were retrieved on 2026-10-06. Four further documents the study tried to retrieve could not be read from this session and are not used. This book was written on 2026-10-07.
Bibliography
- David Gems, The aging-disease false dichotomy: understanding senescence as pathology (2015).
- Andrew J. Scott and others, The economic value of targeting aging (2021).
- David A. Barzilai, Healthy life extension: Geroscience's north star (2026).
- Steve Horvath, DNA methylation age of human tissues and cell types (2013).
- Daniel W Belsky and others, Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm (2020).
- Gregory M. Fahy and others, Reversal of epigenetic aging and immunosenescent trends in humans (2019).
- Julie A. Mattison and others, Caloric restriction improves health and survival of rhesus monkeys (2017).
- R. Waziry and others, Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial (2023).
- Advanced Research Projects Agency for Health, PROSPR: Proactive Solutions for Prolonging Resilience (2025): programme page.
- Carlos López-Otín and others, Hallmarks of aging: An expanding universe (2023).
- Brian K. Kennedy and others, Geroscience: Linking Aging to Chronic Disease (2014).
- Mahdi Moqri and others, Biomarkers of aging for the identification and evaluation of longevity interventions (2023).
- Jamie Justice and others, Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes (2016).
- John C. Newman and others, Strategies and Challenges in Clinical Trials Targeting Human Aging (2016).
- Richard A. Miller and others, An aging Interventions Testing Program: study design and interim report (2007).