When the donor leaves, does the model's consent remain?

The options

The order shown is not a ranking of preference.

1. Option 1

   Continue use within the original scope of consent

   Gains research continuity but relies on consent that did not anticipate new uses.

2. Option 2

   Periodic consent from the individual and successors

   Renews control but excludes cases of death or loss of contact.

3. Option 3

   Public-interest review and benefit sharing by use

   Opens joint control but increases the power of surrogate judgment.

The situation as it stands

In this world, models are built that simulate an individual's physiological responses in fine detail. Decision deadline: 90 days until the next research contract.

Fictional medical research consortium

1. Premise 1In this world, models are built that simulate an individual's physiological responses in fine detail.
2. Premise 2Models of deceased donors are also used in new treatment research.
3. Premise 3Some model responses conflict with the original donor's preferences.

Where it holdsSets the rules for use, revenue, and withdrawal for patient models. It does not settle the assumption that the models have consciousness.

What is still unknown

1. Unknown 1Grounds for reading model responses as preferences or signals
2. Unknown 2Scope of handling research already derived upon withdrawal

Signals to decide again

• Define the observation, owner, and confirmation window that will establish "grounds for reading model responses as preferences or signals," and rejudge when new confirmation changes the tradeoff among the options.
• Define the observation, owner, and confirmation window that will establish "the scope of handling research already derived upon withdrawal," and rejudge when new confirmation changes the tradeoff among the options.